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E., Reakasame S., Silva R., Morais J

Aside from questions regarding the uniqueness of microbes of AD, the observation that AD patients have a poorer oral hygiene that is in part considered due to their declining functional capacity (Gao et al., 2020), suggest that the microbes found in their brains areas as a result of deteriorating mental health and not the cause

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10.1002/path.2277 [DOI] [PMC free article] [PubMed] [Google Scholar] Xue X

This, in turn, boosts metabolic rate and activates a gene known as sirtuin-1 (SIRT1), also referred to as the "longevity gene." SIRT1 is involved in reducing the risk of various conditions such as diabetes, obesity, metabolic syndrome, atherosclerosis, cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer.