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A B12 injection bypasses the gut entirely

Under this alternative pathway, a medical device that has received FDA marketing authorization (that is, has been approved or cleared by, or had a De Novo classification request granted by, FDA) as a Breakthrough Device, for the indication covered by the Breakthrough Device designation, will need to meet the requirements of 412.87(c)

James SH, Kimberlin DW, Whitley RJ

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Folate and vitamin B 12 levels In the whole sample, the median value of folate was 5.3 [3.9, 7.5]ng/ml, and for vitamin B 12 401 [323, 502]pg/ml