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Notably, Central Europe, a region with a high-moderate SDI, had the highest prevalence rate and incidence rate in 2021 at 111 (102.45 to 120.09) and 20.27 (18.55 to 22.09) per 100,000 people, as well as the second highest rate of deaths and DALYs (Figure 2 and Table 1)

The timeline may vary depending on the severity of each case, but it is mandatory to abstain from smoking for a set number of days

One study specifically found a significant association between pack-years (packs per day multiplied by years of smoking) and the severity of ED

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