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Enhanced Antioxidant Protection By neutralizing free radicals, glutathione protects cells from damage that can contribute to chronic diseases

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Transcription factor binding prediction analysis for differentially expressed genes suggested that SIRT3-induced transcriptional changes in aged HSCs was influenced by transcription factors that are involved in the establishment of chromatin accessibility at inflammation-trained loci, such as NF-B, FOS, JUN, GATA1, ATF family members, CREB1, EGR1 and STAT family members (Extended Data Fig

This results in improved body composition with less body fat and more lean muscle mass