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Usaj, M

Pharmacological inhibition of cyclophilin D using cyclosporine A provided only temporary protection in vitro66, but cyclophilin D-deficient mice were protected against liver injury when treated with a moderate APAP overdose of 200 mg/kg68

Originally investigated by researchers for its profound cytoprotective effects on the gastrointestinal mucosaspecifically in the healing of gastric ulcers and inflammatory bowel diseasethe therapeutic potential of BPC-157 has since expanded dramatically into the realms of severe musculoskeletal repair, soft tissue regeneration, and advanced neuroprotection

3 , e12383 (2021)

Furthermore, restoration of cellular GSH status could prove to be of therapeutic benefit in patients with a GSH deficiency associated with their ETC defects