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Calcium signaling in mitochondrial intermembrane space

The demonstration that OEA is the most active endogenous ligand for GPR119 is of particular interest since previous work has demonstrated that OEA, when administered to laboratory animals, causes a significant reduction in food intake and body weight gain

Many foods are fortified with artificial vitamin B12, such as non-dairy milks and cereals, but these are not always optimally absorbed, so vegans must still be proactive about making sure they are not becoming deficient

We thank K Hultenby and E Idsund Jonsson for their expertise in preparing tissues and aquiring TEM images at EMiL

While there are treatments available to alleviate some of the symptoms and reduce the frequency of relapses, many patients still progress into a secondary phase of the disease, which steadily worsens over time, causing severe disability