Clinical trials at doses up to 40mg daily for 12 weeks have reported no serious adverse effects (Brendler & Williamson, 2019, Phytomedicine )
However, neither Fer-1 nor QCT could reverse the reduced embryo survival rate, FGR (i.e., reduced crown-rump length and fetal weight), and placental abnormalities (e.g., decreased placental diameter and weight) (Supplementary Fig
It's one of the most commonly studied doses, it's generally well tolerated, and it provides flexibility to increase intake later if a higher amount is appropriate.1 35 That flexibility is particularly valuable given the uncertainties surrounding NAC and cancer biology discussed above

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Consistent with our prior publication, 42 subchronic sCT treatment then caused a reduction in body weight in RAMP 1/3 KO mice but resulted in a modest weight gain of approx