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it can survive and remain active across the highly variable pH levels of the human gastrointestinal tract, from the highly acidic environment of the stomach to the more alkaline environment of the small intestine

Wnt signaling blockage inhibits cell proliferation and migration, and induces apoptosis in triple-negative breast cancer cells

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What is measured in these rats and mice (and occasionally in small groups of human volunteers) is often not a hard endpoint like muscle strength or weight loss, but surrogate biomarkers: molecules in the blood that have an indirect link to a hard endpoint