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Research indicates that NAC can regualate autophagy and promote the clearance of -amyloid proteins [258], an effect that may relate to its capacity to scavenge one-electron oxidants [259], thereby positioning NAC as a potential therapeutic strategy for Alzheimers disease

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XBP1 inhibits mesangial cell apoptosis in response to oxidative stress via the PTEN/AKT pathway in diabetic nephropathy

NUTRITIONAL SCORE: 54 71

On day 4, 48 h post-transfection, cells were treated with the ferroptosis-inducing compounds erastin, RSL3, or FINO2 in the presence or absence of Ferrostatin-1 (Fer-1) as indicated