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Therefore, we chemically synthesized the relevant macrocycles with C-terminal (-alanine) 2 -FLAG tags (A 2 -FLAG), with the resulting peptides referred to as aML5-FLAG, aMD4-FLAG and aMD5-FLAG (Supplementary Table 2 and Supplementary Fig

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Plain sterile water is not preservative-free bacteriostatic once the vial seal is broken, it is susceptible to microbial contamination and should only be used for single-draw applications

In vitro functional assays, including luciferase and cAMP assays, were performed on cell lines expressing human and rat amylin and calcitonin receptors