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TFAs formed during the industrial hydrogenation of vegetable oils are believed to distort phospholipid composition of the brain membrane, increasing membrane rigidity and hence affecting neuronal signaling (Figure 9)

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Plant J 64:825838 Distfano AM, Martin MV, Crdoba JP, Bellido AM, DIpplito S, Colman SL, Soto D, Roldn JA, Bartoli CG, Zabaleta EJ, Fiol DF, Stockwell BR, Dixon SJ, Pagnussat GC (2017) Heat stress induces ferroptosis-like cell death in plants