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Thus, with such a background (i.e., useful modulation/control of the increased angiogenesis, elevated VEGF levels, upregulation of the egr-1 gene, enhanced NO and eNOS stimulation, and counteraction of increased free radical formation), stable gastric pentadecapeptide BPC 157 is working as a cytoprotective agent (and, therefore, with a highly postulated safety profile) (and not as a panacea effective for all conditions)

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Molecular size affects absorption, with smaller peptides generally crossing the mucosal barrier more easily than larger ones