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In some embodiments, the otic formulation or composition comprises between about 0.01% to about 20% by weight of the povidone

, they had to be preceded by the already advanced significant damage in the brain), the seizures lasted for a few hours throughout the progressing brain and liver damage (as seen with worsening throughout the 3-24 h post-paracetamol period)

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Imaging and single-cell RNA sequencing reveal that TfR1-targeted ATVs localize mainly to neurons and astrocytes, while CD98hc-targeted constructs show broader astrocyte and microglia uptake

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