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Cigarette smoke is made up of more than 7,000 toxic chemicals, including ammonia, tar, and carbon monoxide

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It is well-known that pro-inflammatory cytokines that induced chronic inflammatory response have to be considered as two potent activators of pro-oncogenic signaling that were linked to HCC onset 136 , such as IL-6 prevents DNA-damage-induced hepatocyte apoptosis through suppression of p53 and enhances -catenin activation 137

The cost of smoking covers not only hospital admissions but also factors such as social care

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