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P values were considered statistically significant if lower than 0.05

1213 expresses condolences to the loved ones of fallen law enforcement officers, acknowledges the tremendous difficulties law enforcement officers face, and condemns calls to defund the police

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Headaches (18%) and bad breath (15%) were the most frequently reported side effects, although 23% reported no symptoms

Also, it has also been reported that CNS drugs utilize similar nicotine transport systems at the BBB interface, and in the presence of nicotine, their transport to the brain can be directly affected (Tega et al., 2018)