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FIGURE 4 3.4 Nitazoxanide reduced apoptosis in rats with MTX-hepatotoxicity MTX significantly induced hepatic apoptosis as demonstrated by increased proapoptotic markers, Bax level, and caspase-3 activity (Figures 5A, D) while reduced antiapoptotic Bcl-2 level (Figure 5B) and increased Bax/Bcl-2 ratio (Figure 5C) compared to CTRL group

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This is because it can help to stimulate the production of collagen and elastin, two proteins that are essential for maintaining skin elasticity and firmness Hyaluronic acid (HA) is a naturally occurring substance in the skin that helps to keep it hydrated and plump

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