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This article covers the key milestones in glutathione's scientific journey, the mechanism that makes it uniquely powerful among antioxidants, and why it took nearly a century for medicine to recognize what yeast cells were doing all along

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Importantly, novel drug delivery technologies, particularly ROS-responsive and mitochondria-targeted nanocarriers, as well as synergistic co-delivery systems, offer promising solutions to challenges such as its low bioavailability

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