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They are polarized tissues due to the differential expression of ion channels, pumps and transporters in the apical and the basolateral sides: (a) epithelial sodium channels (ENaC), Ca 2+ activated chloride channels and the cystic fibrosis transmembrane conductance regulator (CFTR) are present in the apical plasma membrane and (b) the Na + -K + -ATPase ion pump and the Na + -K + -2Cl cotransporter in the basolateral side

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Wang L, Wang N, Zhang W, et al.: Therapeutic peptides: Current applications and future directions

Typically, MIC B12 injections are administered once or twice a week to maintain their benefits

This section summarizes current research progress on mitochondrial biogenesis, mitophagy, and mitochondrial dynamics in common neurodegenerative diseases (AD, PD, HD, and ALS) (Figure 5)