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Microsomes were suspended in 0.1M Tris buffer (pH 7.38) at 0.5 mg/mL and 100 , of the microsomal suspension was added to pre-chilled microcentrifuge tubes on ice

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Parameters noted were the concentration of test substance providing maximal fold induction of luciferase (C max ), and the maximal fold induction observed (FI max ).FIG

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[DOI] [PubMed] [Google Scholar] 47.Turkovic B, Sikiric P, Seiwerth S, Mise S, Anic T, Petek M, Rucman R