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doi: 10.1146/annurev.genom.1.1.507 157 MahleyR

However, a one-year randomized, double-blind, placebo-controlled trial in 253 elderly (65 years) adults with elevated homocysteine levels found that B vitamin supplementation (1,000 g/day of folate, 10 mg/day of vitamin B 6 , and 500 g/day of vitamin B 12 ) did not improve measures of cognitive function, including memory, despite lowering homocysteine levels (116)

Finally, we did not evaluate differences in adaptive functioning among the autistic disorder, Asperger syndrome, and TD groups

10.1016/j.mbs.2014.07.013 Math Biosci