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Reactions catalyzed by different strains of gut bacteria include ( 1 ) A-ring reduction, ( 2 ) reduction of the 5 -double bond, ( 3 ) reduction of 17-keto estrogens and 17-keto androstenes, ( 4 ) 17,20-cleavage of 17-hydroxysteroids, and ( 5 ) 16- and 21-dehydroxylation (Fig

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We would also like to thank the Genomics Research Center (GRC), the Histology, Biochemistry, and Molecular Imaging (HBMI) Core at the Center for Musculoskeletal Research (CMSR), and the Center for Advanced Research Technologies (CART) at URMC, the Bauer Core Facility at Harvard University, and Proteomics/Metabolomics Core at Moffitt Cancer Center, which is funded in part by Moffitts Cancer Center Support Grant (P30CA076292)

Neither of the component amino acids is sweet (Phe is actually bitter), and derivatives of the other dipeptide (Phe-Asp) are not sweet