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[11] Tirzepatide is a prescription medication approved by the FDA for the treatment of type 2 diabetes (under the brand name Mounjaro) and chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity (under the brand name Zepbound)

Despite the substantial enhancement of visual outcomes provided by existing therapies for AMD, especially anti-VEGF drugs, their prolonged application is constrained by exorbitant costs, the necessity for recurrent intravitreal injections, inconsistent patient responses, and possible bad effects

This is a stressor for the body, causing hypoxia of intestinal cells due to redistribution of blood in the body, hyperthermia and dehydration [158, 159]

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