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The combination may reduce gut inflammation on multiple levels, including systemically, via cytokine signaling, and through modulation of the intestinal immune response
Side Effects & Safety Injection site reactions -- redness, swelling, stinging (common with large-volume SC injections) Flu-like symptoms -- mild fever, fatigue, malaise 24-72 hours post-injection (possibly from immune clearance of apoptotic cells) GI discomfort -- nausea, mild digestive upset Temporary fatigue -- 1-3 days post-injection Off-target cell death (theoretical) -- no compound is perfectly selective
Despite some promising findings, particularly in those with noise-induced tinnitus, gabapentins usefulness in tinnitus has not been clearly demonstrated
y Koch, RJ (2005)