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The oral daily dose far exceeds the vitamin requirement because the normal transporter protein-mediated absorption is absent, leaving only very inefficient intestinal passive absorption

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study

In rats given BPC-157, serotonin levels in the brain increase in specific regions while simultaneously decreasing in other regions, such as the hippocampus.[ref] A 2020 study found that BPC-157 reduced leaky gut syndrome by stabilizing gut permeability after NSAID use.[ref] Reducing leaky gut theoretically can affect the gut-brain axis and reduce inflammation