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In general, chronic exposure to nicotine may cause an acceleration of coronary artery disease, peptic ulcer disease, reproductive disturbances, esophageal reflux, hypertension, fetal illnesses and death, and delayed wound healing

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Pulmonary Embolism Although less common, smoking increases the risk of blood clots, which can travel to the lungs and cause a pulmonary embolism (a blockage in the lungs arteries)