In terms of weight loss, if you have a vitamin B12 deficiency, which is likely, you will lose some of the vitamin B12 shot in the first 48 hours, but at least 50% of it will be stored in your liver
While animal foods and fortified products contain B12, excess amounts are normally eliminated
For patients without neurological involvement , hydroxocobalamin 1 mg is administered intramuscularly three times a week for 2 weeks, followed by maintenance injections every three months for life (if due to pernicious anaemia or other non-dietary cause)

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10.1007/s10067-014-2736-6 [DOI] [PubMed] [Google Scholar] 3.Siracusa R, Paola RD, Cuzzocrea S, Impellizzeri D