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11 The anatomical linchpin is the area postrema, a small hindbrain structure that sits outside the bloodbrain barrier and is therefore directly exposed to circulating hormones

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Hydroxocobalamin is the preferred agent in this patient population (see separate monograph in Less Common Drugs)

A study conducted at the New York University School of Medicine showed that even mild traumatic brain injury caused brain atrophy, and most of this damage was due to the disrupted glutamine-glutamate cycle and an abnormal increase in glutamate levels

It matters more than most patients expect