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On the other hand, deficient cortisol levels, also known as hypocortisolism or Addison's disease, can also affect methylation and detoxification

Commonly used reducing agents include TCEP, DTT, and bME

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Three pharmacokinetic (PK) studies (total of 30 patients) have suggested that those with Gilberts syndrome have lower paracetamol glucuronidation [28, 33, 34]