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Firstly, cells of both innate and adaptive immunity, as well as a wide range of non-hematopoietic cells, activate the release of Transforming Growth Factor- and several pro-inflammatory cytokines such as IL-1, IL-6, and IL-23 ( Figure 5 )

Nutritional Neuroscience , 19 (8), 346351

doi: 10.1155/2013/270418 22

This is consistent with the typical structure and function of the CREB1/CRTC2 complex

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