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This protective mechanism extends to the scalp, where selenium helps maintain optimal conditions for hair growth by reducing inflammation and supporting cellular health

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The future lies in developing allosteric modulators or subunit-selective antagonists (particularly for GluN2B-containing receptors) that can precisely modulate pathological hyperactivity in the auditory pathway without disrupting essential NMDA receptor functions elsewhere in the brain, thereby offering a more effective and tolerable treatment strategy for tinnitus (Rafe et al., 2024

Theyre also among the most vulnerable structures to free radical damage