We reduced the dimensionality of the chromatin accessibility data by latent semantic indexing, by first normalizing using the term frequency-inverse document frequency (TF-IDF) normalization method, followed by a singular value decomposition using all peak features implemented in Signac
Abstract Background Trace elements dyshomeostasis affects the physiological processes, metabolism, and immune function and leads to systemic and localised pathologies such as diabetes, cancer, and ocular degenerative diseases
Kiernan F
In 3xTg AD mice, we found that a reduction of calories without a prolonged fast improves glucose tolerance and aspects of AD pathology, reducing the density of A plaques and neuroinflammation, but did not improve tau pathology
REGULATION OF SULFATE TRANSPORT Sulfate uptake plays a major role in the control of plant sulfur homeostasis (Vauclare et al., 2002)