Glutathione has two mutually interconvertible forms, reduced glutathione (GSH) and oxidized glutathione (GSSG)
We further treated multiple types of cancer cell lines, including breast cancer (MCF7), pancreatic ductal adenocarcinoma (MIA Paca-2), colon cancer (SW116, HCT116, Caco2) and lung cancer (H5889) cells
Increased risk of inconsistent results for RCTs suggests higher prevalence of bias, which may arise due to many issues including design bias, conflicts of interest, treatment differences by physicians aware of allocation, attrition bias, ascertainment bias, randomization failures, errors, or fraud
They reduce hydrogen peroxide and organic hydroperoxides to water or alcohols by oxidizing GSH to GSSG
Propylthiouracil blocks extrathyroidal conversion of thyroxine to triiodothyronine and augments thyrotropin secretion in man