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(December 1996)

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Low toxicity, resistances to hydrolysis and low protein adsorption make suitable for drug delivery system such as hydrogels, micelles, nanoparticles and also polymer drug conjugates for various applications including tissue engineering and biofouling resistance coating for medical devices [73,74,75]

The enzymes catalyzing the reactions are as follows: glucose-6-phosphate isomerase (GPI), mannose-6-phosphate isomerase (PMI), phosphomannomutase (PMM), GDP-mannose pyrophosphorylase (GMP), GDP-mannose-3,5-epimerase (GME), GDP-L-galactose phosphorylase (GGP), L-galactose-1-phosphate phosphatase (GPP), L-galactose dehydrogenase (GalDH), L-galactono-1,4-lactone dehydrogenase (GalLDH), ascorbate peroxidase (APX), monodehydroascorbate reductase (MDHAR), dehydroascorbate reductase (DHAR), ascorbate oxidase (AO), and glutathione reductase (GR)