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Research shows BPC-157 protects cells from various forms of stress including ischemic injury, oxidative damage, and toxic insults

In some embodiments, the otic formulation or composition comprises between about 0.01% to about 2% by weight of the carbomer

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This results in more targeted, potent effects with faster, more measurable improvements in performance metrics

In addition, expanded ATXN3 proteins tend to accumulate in the nucleus, where the high protein concentration facilitates its abnormal interactions with transcription factors and cofactors, with histone deacetylases and with regulatory sequences of the DNA [55, 111, 113,114,115,116]