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GHK-Cu (copper tripeptide-1) is a cosmetic ingredient with a fifty-year topical research history and no approved injectable product, no published human injection trial, and no established parenteral dose in the peer-reviewed literature

As a result, direct oral GSH administration does not result in significant systemic elevation of GSH levels, curbing its utility in treating neurodegenerative diseases

We then examine several compounds capable of promoting NRF2 activity thereby inducing cytoprotective effects, and which are currently in different stages of clinical development for many pathologies, including neurodegenerative diseases

Archivos de medicina 2009;5(1:5)

Molecules, 19(11), 19066-19077