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It is also being investigated for cognitive benefits and improved metabolic function in experimental settings

One hallmark example is capecitabine-induced diarrhea , which results from its conversion to 5-fluorouracil (5-FU) in the gastrointestinal mucosa via thymidine phosphorylasean enzyme that is upregulated in tumor and normal epithelial tissues

[DOI] [PMC free article] [PubMed] [Google Scholar] Liu Z, Guo J, Sun H, Huang Y, Zhao R, Yang X

In improving cardiac systolic and diastolic function, a study has found that ginsenoside Rg3 can significantly inhibit the proliferation of middle vascular smooth muscle cell proliferation, reduce stromal hyperplasia, and enhance vasodilation and vasoconstriction function in elderly rats (Liu et al., 2016)

The developed NO-releasing biomaterials can release NO under various stimuli, such as metal ions, enzymes, heat, and light irradiation, and photothermally induced NO release can be combined with photothermal therapy in biomedical applications