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This cell danger response is an evolutionary adaptation enabled to protect the cells and host from harm (414416)

113 In the canonical Wnt/-catenin pathway, the protein destruction complex (adenomatous polyposis coli [APC], casein kinase 1 [CK1], glycogen synthase kinase 3 [GSK-3], and axis inhibition proteins [AXINs]) targets and phosphorylates the -catenin protein

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