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In 2014, the Royal College of Physicians published a statement that suggested they were an effective and affordable alternative to conventional cigarettes and could make harm reduction a reality for smokers. The American Lung Association heralded the news as a long-awaited step to protect public health. At last the Food and Drug Administration will have basic authority to make science-based decisions that will protect our nations youth and the public health from all tobacco products, including e-cigarettes, cigars and hookah, Harold Wimmer, president and CEO of the association, said in a statement

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Leventhal AM, Strong DR, Kirkpatrick MG, et al

Cytoskeletal modulation and tyrosine phosphorylation of tight junction proteins are associated with mainstream cigarette smoke-induced permeability of airway epithelium

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