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Phenotype prediction The detection of patients in the neonatal period before developing symptoms has increased the need for reliable phenotype prediction

10.1001/archpsyc.1997.01830220033006 4 AlmullaA

Without the BBB, the CNS is at risk of invasion of toxins, pathogens, immune cells, or ion dysregulation, which would lead to neuronal dysfunction and degeneration [1]