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These factors can exacerbate disease severity, leading to increased morbidity and a reduced quality of life 13

Feb 2 2008;371(9610):395-403

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10.1038/264247a0 Summary Keywords prenatal therapy, in utero transplantation, sickle cell disease, tregs, congenital blood disorders, haematopoietic stem cell transplantation (HSCT) Citation Cortabarria ASV, Makhoul L, Strouboulis J, Lombardi G, Oteng-Ntim E and Shangaris P (2021) In utero Therapy for the Treatment of Sickle Cell Disease: Taking Advantage of the Fetal Immune System