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It is characterized by a persistent rise in arterial BP, leading to serious health problems such as CHD, stroke, sudden cardiac death, congestive heart failure (CHF), renal insufficiency (RI), and dissecting aortic aneurysm (9, 10)

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Depletion of GSH can lead to, among other things, mitochondrial dysfunction and cell death

Randomized phase II study of erlotinib in combination with placebo or R1507, a monoclonal antibody to insulin-like growth factor-1 receptor, for advanced-stage non-small-cell lung cancer

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