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Collectively, the inflammatory stress, the decrease in miR-122 and associated hyperinsulinemia in NASH presents a reasonable explanation for the constant activation of SREBP2 bypassing the canonical negative feedback inhibitory effect of high levels of cellular cholesterol (37)

Overexpression of FSP1 effectively inhibited ferroptosis in HT1080 cells but failed to inhibit ferroptosis in COQ2-deficient cells, which indicates that the anti-ferroptosis effect of FSP1 is dependent on CoQ10

Spielmann, A

Effect of synthetic peptides on aging of patients with chronic polymorbidity and organic brain syndrome of the central nervous system in remission

10.1016/j.envint.2004.10.001 26 alikanM