Whitbread JS, Murphy KJ, Clifton PM, Keogh JB
Chromatin immunoprecipitation demonstrated a marked enrichment of H4K5la at the COL1A1 promoter, driving its transcription and promoting extracellular-matrix remodeling, actin reorganization, and aggressive tumor proliferation and invasion
Questions and Answers Questions Abbreviations used: AFP, alpha fetoprotein ALP, alkaline phosphatase ALT, alanine aminotransferase AMA, antimitochondrial antibody ANA, antinuclear antibody anti-HAV, antibody to hepatitis A virus anti-HBc, antibody to hepatitis B core antigen anti-HBs, antibody to hepatitis B surface antigen anti-HCV, antibody to hepatitis C virus anti-LKM, antibody to liver-kidney microsome type 1 ASMA, antismooth muscle antibody AST, aspartate aminotransferase BCLC, Barcelona Clinic Liver Cancer BCS, Budd-Chiari syndrome BMI, body mass index CBC, complete blood cell count CT, computed tomography DAA, direct-acting antiviral DILI, drug-induced liver injury EGD, esophagogastroduodenoscopy ERCP, endoscopic retrograde cholangiopancreatography FISH, fluorescence in situ hybridization GAVE, gastric antral vascular ectasia HAV, hepatitis A virus HBsAg, hepatitis B surface antigen HBV, hepatitis B virus HCC, hepatocellular carcinoma HCV, hepatitis C virus HE, hepatic encephalopathy IBD, Ig, INR, LDL, MCV, MELD, MRCP, MRI, NAFLD, NASH, NSBB, PBC, PMN, PSC, SMA, TIPS, WBC, inflammatory bowel disease immunoglobulin international normalized ratio low-density lipoprotein mean corpuscular volume Model for End-stage Liver Disease magnetic resonance cholangiopancreatography magnetic resonance imaging nonalcoholic fatty liver disease nonalcoholic steatohepatitis nonselective -blocker primary biliary cholangitis polymorphonuclear neutrophil primary sclerosing cholangitis smooth muscle antibody transjugular intrahepatic portosystemic shunt white blood cell count Multiple Choice (choose the best answer) VI.1
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other weight-loss drugs Eloralintide is still being tested, so its too early to compare it directly to medications like Wegovy or Zepbound
