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Acknowledgements We thank Lauren Knightley, Beth Jago, Meirion Richards, and Amin Mirza of the Structural Chemistry team for their expertise and assistance, Swen Hoelder for his continuous support, Stephen Hearnshaw for his contributions to crystal optimisation, and Chris Richardson for crystallography computing support

Alternative treatments for receding gums include gum grafting, periodontal therapy, connective tissue grafts, scaling and root planing, and the use of orthodontic appliances to reposition teeth

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Gramer G, Hoffmann GF (2020) Vitamin B12 deficiency in newborns and their mothersnovel approaches to early detection, treatment and prevention of a global health issue

The idea that a days difference is inconsequential is a misconception that fails to recognize the debilitating nature of the symptoms (fatigue, neurological issues, etc.)