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98.6% (138/140) in EPG of over 100

When formulated together, niacinamides anti-inflammatory and barrier-strengthening properties help improve tolerability of tretinoin, reducing common side effects like dryness and irritation

A membrane-free gut-on-chip study revealed that candidalysin disrupts tight junction proteins (ZO-1, occludin) to induce leaky gut, and further induces intestinal epithelial cells (IECs) apoptosis and necroptosis, thereby exacerbating barrier breakdown 111

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