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Reported adverse effects included mild injection site reactions and transient headaches

SELECT Trial Investigators

Radiolabeled somatostatin analogs generally comprise three main parts: a cyclic octapeptide (e.g., octreotide), a chelator (e.g., DTPA or DOTA), and a radioactive element (111In, 90Y, or 177Lu)

Early-phase clinical trials including a Phase 2 dose-ranging study published in the New England Journal of Medicine (2023) have demonstrated significant potential for weight reduction and metabolic improvement, generating considerable scientific interest