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With the recent connection between the BBB and gut microbiota, microbial-derived metabolites have been explored for their capabilities to protect and restore BBB physiology

Aura Phase: Auras, experienced by a subset of migraine sufferers, are transient sensory disturbances that often affect vision with symptoms like flashing lights, blind spots, or geometric patterns

We defined S to be a factor multiplying the V max values of GCL and GPX representing the activation of GCL and GPX, so S = 1 for males and S = 1.8 for females for average estradiol, since we make a case based on experimental and clinical results that the activation is by 80%

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