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Alterations in microbial communities and their metabolites have been linked to key pathological features of PCOS (116, 117), including insulin resistance, hyperandrogenism, and chronic low-grade inflammation, supporting the concept of a gutmetabolismreproductive axis in which intestinal microbial ecosystems influence both metabolic and endocrine homeostasis (104)

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mTOR has emerged as a crucial control point for B cell functions 35

Individuals with the chronic hemolytic G6PD variants have varying degrees of anemia and reticulocytosis

Zhang, Y., Zheng, D., Fang, Q