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Rotate sites systematically (abdomen at least 2 inches from navel, thighs, upper arms) to avoid lipohypertrophy [8]

This represents a shift from "preclinical only" to early-stage clinical investigation

That holds even for people who would not otherwise have difficulties

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Therefore, HSA is recommended for managing hypoproteinemia in cardiac surgery, mitigating complications such as renal insufficiency [125,126]