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Nicotinamide adenine dinucleotide (NAD + ) is a vital cofactor in mitochondrial bioenergetic pathways, including glycolysis, fatty acid -oxidation, and the TCA cycle 517

designed intelligent drug-delivery NPs, Co-Fc@HCQ, which are composed of cobalt-ferrocene-based MOF materials (Co-Fc) loaded with the autophagy inhibitor hydroxychloroquine (HCQ)

[21] [22] Studies of progeroid (premature aging) syndromes, which mimic the clinical and molecular characteristics of aging, have provided some insight into the mechanism of action of NAD+ replenishment

Shuvalova YA, Kaminnyi AI, Meshkov AN, Kukharchuk VV